Your Soft-Landing into the U.S.

U.S. Market Gateway Accelerator for BioSciences and MedTech

Fall 2025: September 8 - October 30, 2025
8-week Hybrid Program

We take the uncertainty out of U.S. market entry

Entering any new market comes with a variety of opportunities and challenges for scaling companies. To gain fast traction and reliable growth in the U.S., international companies need both exceptional strategy and execution. This program provides that and is delivered in four modules.

Four Modules are presented in 12 sessions with experts on Legal Aspects, U.S. Healthcare, Operations in the U.S., and Fundraising and Business Communication. Six one-on-one sessions with mentors provide guidance, in-depth strategy discussions, and new contacts.

The U.S. Market Gateway Accelerator culminates with the opportunity to pitch to a panel of Angel and VC investors, and visit major local medical centers in the greater Philadelphia ecosystem.

Statistically, only one in five companies succeeds in expanding to the U.S. market. Our success rate shows that we will double your odds.*

Medtech and Life Science Focus

Legal Aspects
Incorporation – How U.S. company structures align with investor expectations.
IP Protection – Why U.S. IP strategy differs from other global systems.
Immigration – Navigating founder and key staff visas to support expansion.

U.S. Healthcare
Reimbursement Strategies – Understanding how payers drive adoption.
Regulatory Issues – What U.S. agencies require to reach the market.
Marketing to Patients, Providers, and Payers – Tailoring your approach to each key stakeholder group.

Operations in the U.S.
Finding & Hiring Talent – Building the right team for U.S. growth.
Site Selection & R&D Credits – Choosing locations that maximize incentives.
Banking, Accounting & Taxation – Structuring finances across borders.

Fundraising and Business Communication
Cultural Differences – Avoiding missteps when working with U.S. partners.
Investor Expectations – What American investors look for before funding.
Sources of Funding & Pitch Structure – Targeting the right capital and communicating effectively.

  • “The accelerator delivered! It may be called Soft-Landing, but it felt like we were flying; the tightly paced sessions followed by in-depth mentoring really prepared us for our U.S. expansion. The program delivered months of work in only a few days, an incredible value!”

    David Contoir-White, Co-founder Modulari-T Bio

  • "WorldUpstart provided us with the most impactful strategy for U.S. entry and would have saved us lots of sleepless nights if we had begun our engagement sooner."

    Alison Sundset, CEO of HoloCare

  • “Advice and mentoring from the biggest players in Pharma. If you’re serious about entering the U.S. market you have to be in the program! I would never have dreamed of having access to companies like JP Morgan and Merck, but thanks to the Accelerator I did! We now know what we need to know.”

    William Purvis, CinchOrtho

  • “This program is very insightful, and all speakers and mentors are very committed and willing to spend more time answering our questions. The program is useful for companies starting to explore the U.S. environment as well as for companies already engaged in U.S. development. I definitely recommend!”

    Marion Marini, Co-founder of Alcediag

  • “The program provided us with all the desired and required information to fully understand the roadmap to the U.S. market and its regulations. Moreover, the direct access to some investors perspectives in open friendly discussions made us better understand the perspective on potential financial partnering for this specific market. On behalf of StemAxon TM, we want to express our gratitude and many thanks on such a knowledgeful program.”

    Alain Rheault, Co-founder of StemAxion

If your company is considering or ready to expand to the U.S. market and has demonstrated market traction in your own country or other regions, and/or has sufficient funding for market expansion, this program is for you!

By the end of our eight-week online program with subject matter experts, weekly meetings with industry leader mentors, and in-person sessions, you will gain the strategy, connections, and roadmap for a successful entry to the U.S. market.

In addition to the U.S. Market Gateway Accelerator program, companies can engage WorldUpstart to help them with pitch coaching; introductions to investors; engaging with students from local universities on company-specific strategic research; providing targeted business development consulting for expansion to Philadelphia, Boston, or other markets.