Brianna Amato 5/13/26 Brianna Amato 5/13/26

You’re Not Expanding to the U.S., You’re Starting Over

Brianna Amato 4/6/26 Brianna Amato 4/6/26

Why the best U.S. entry point may not be the biggest one

Karina Sotnik 12/2/25 Karina Sotnik 12/2/25

Philadelphia: A Global Gateway for Life Sciences Expansion to the U.S.

The article also outlines how international companies can position themselves for successful U.S. expansion. For Life Science and MedTech founders around the world, entering the U.S. market is one of the most important and most challenging strategic decisions they will make. The United States remains the world’s largest healthcare market, but its complexity requires a clear understanding of regulatory pathways, reimbursement structures, clinical partners, and commercialization realities. Choosing the right starting point in the U.S. can dramatically influence a company’s trajectory.

Karina Sotnik 11/26/25 Karina Sotnik 11/26/25

From Uncertainty to Strategy: How to Evaluate Your U.S. Market Timing

If you’re a CEO of a Life Science or MedTech company in Europe, Asia, or elsewhere in the world, you’ve probably asked yourself—more than once: "Should we expand to the U.S. right now? What if the timing is wrong? What if the market is too complex? What if we’re not ready?" Here’s practical guidance for CEOs navigating this decision in an uncertain global environment.

Samantha Carroll 11/5/25 Samantha Carroll 11/5/25

Global Innovators Take the Stage at the WorldUpstart Accelerator Showcase in Philadelphia

WorldUpstart welcomed its 10th international cohort of startups to Philadelphia for a high-impact, in-person Industry Showcase, spotlighting groundbreaking innovations from eight global life sciences, MedTech, and Digital Health startups, representing Korea, France, Ecuador, and New Zealand.

Stephanie Vogel 8/5/25 Stephanie Vogel 8/5/25

🌍 WorldUpstart Newsletter | Summer 2025

Stephanie Vogel 5/5/25 Stephanie Vogel 5/5/25

From Global to Local: Greater Philly Ecosystem Accelerates International Life Sciences Growth

WorldUpstart is proud to welcome the latest cohort of international life sciences, medtech, and digital health companies to Philadelphia for its flagship U.S. Market Gateway Accelerator Showcase, a two-day event designed to connect high-potential global innovators with investors, industry partners, and key stakeholders in the U.S. healthcare ecosystem.

Stephanie Vogel 10/28/24 Stephanie Vogel 10/28/24

Global Innovation Meets Local Ecosystem: PHL MedTech and Life Sciences Showcase

Philadelphia is emerging as a top destination for international startups entering the U.S. healthcare market, thanks to the success of WorldUpstart’s U.S. Market Gateway Accelerator. The program has supported 74 companies from 18 countries, connecting them with Philadelphia’s vibrant Life Sciences and MedTech ecosystem.

Stephanie Vogel 6/12/24 Stephanie Vogel 6/12/24

From Patents to Partnerships: Intellectual Property Tactics for MedTech and Life Sciences Growth in the U.S.

For over three years, WorldUpstart has been at the forefront of assisting BioSciences and MedTech companies from around the globe in successfully entering the U.S. market. With our focused expertise and extensive network, we have helped numerous firms navigate the complexities of market entry, bringing the right tools and knowledge to ensure success. This blog post draws on the deep expertise of Christopher Halliday from DLA Piper, our leading expert in IP protection and strategy, to provide invaluable insights for companies looking to secure their intellectual property while expanding into the U.S. market.